ABOUT METHADONE INITIATION GUIDELINES

noted that rifampicin improved the metabolism of R- and S-methadone while the CYP3A selective inhibitor troleandamycin didn't have any effect within the enantiomers.When put together use is required, consider minimizing doses of one or more drugs. Usage of sodium oxybate with alcohol or sedative hypnotics is contraindicated. Consider therapy modifi